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Avoid Extreme Calorie Restriction: Hormones can get disrupted and period irregularities to occur as a result of extreme weight loss

"Weight Management Programs and Services." kp.org

Structurally, it shares 94% sequence homology with human GLP-1 but includes two critical modifications: the substitution of amino acids to prevent enzymatic degradation by Dipeptidyl Peptidase-4 (DPP-4), and the addition of a C-18 fatty di-acid side chain

Treatment starts at 2.5 mg and increases by 2.5 mg every four weeks until reaching the maximum tolerated dose

In a 2024 real-world study of 40 adults, the average maintenance dose was 1.0 mg in 16 cases and 2.0 mg in 9 cases